@charset "UTF-8";
/*--------------------
 * moderate common
 *--------------------*/

.moderate .under-right, .moderate .under-right .under-content {
  position: relative;
  overflow: hidden;
}

.nav5>a, .moderate h1, .moderate .subnav .title {
  font-family: "heisei-maru-gothic-std", sans-serif;
  font-weight: normal !important;
}

.moderate h1 {
  text-shadow: 0 0.005em 0 #299eac, 0.005em 0 0 #299eac, 0 -0.005em 0 #299eac, -0.005em 0 0 #299eac, -0.005em -0.005em 0 #299eac, 0.005em -0.005em 0 #299eac, -0.005em 0.005em 0 #299eac, 0.005em 0.005em 0 #299eac;
}

.nav5>a {
  padding: 13px 0 9px !important;
  line-height: 1.15;
  -webkit-text-stroke: 0.025em #299eac;
  text-shadow: 0 0.005em 0 #299eac, 0.005em 0 0 #299eac, 0 -0.005em 0 #299eac, -0.005em 0 0 #299eac, -0.005em -0.005em 0 #299eac, 0.005em -0.005em 0 #299eac, -0.005em 0.005em 0 #299eac, 0.005em 0.005em 0 #299eac;
}

@media only screen and (max-width: 640px) {
  .nav5 a br {
    display: none;
  }
  .nav5 a {
    padding: 18px 0 13px !important;
    font-size: 1.1em;
  }
}

.moderate .under-right h2:nth-of-type(1) {
  overflow: hidden;
  font-size: 26px;
  min-height: 44px;
  margin-bottom: 10px;
  padding-top: 14px;
  line-height: 1.4;
  color: #eb566d;
  background: none;
  text-align: left;
  margin: 0 0 30px;
  padding: 0;
}

.moderate .under-wrap .under-right h2 {
  line-height: 1.3;
}

@media only screen and (max-width: 640px) {
  .moderate .under-wrap .under-right h1 {
    font-size: 18px;
  }
  .content-wrap .under-wrap .under-right h2 {
    margin: 2.5% 0;
  }
  .moderate .under-right h2:nth-of-type(1) {
    font-size: 15px;
    padding: 0 10px;
    min-height: auto;
  }
}

.moderate .under-wrap .under-right h3 {
  margin: 40px 0 20px;
}

.moderate h4 {
  color: #299eac;
  line-height: 1.8;
  clear: both;
}

@media only screen and (max-width: 640px) {
  .moderate h4 {
    font-size: 16px;
    padding: 0 10px;
  }
}

.moderate h4:before {
  content: "";
  display: inline-block;
  width: 15px;
  height: 15px;
  border-radius: 50%;
  background: #299eac;
  margin: 0 7px 0 0;
}

.moderate h5 {
  background: #299eac;
  color: #fff;
  padding: 15px 15px 10px;
  border-radius: 10px;
  border: 2px solid #299eac;
  box-sizing: border-box;
  margin: 40px 0 15px;
}

.moderate ol {
  background: #FFF;
  margin-bottom: 20px;
  padding: 20px 20px 15px 20px;
  border: 2px solid #299eac;
  -moz-border-radius: 8px;
  -webkit-border-radius: 8px;
  border-radius: 8px;
}

.moderate dd ol {
  padding: 0;
  margin: 0;
  border: 0;
}

.moderate ol li {
  text-indent: -1em;
  padding: 0 0 0 1em;
}

.moderate li, .moderate dt, .moderate dd {
  line-height: 1.8;
}

.moderate sup {
  color: #eb566d;
}

.moderate .under-wrap .under-right .under-content p:not(:last-child) {
  margin: 0 0 15px;
}

.moderate .under-wrap .under-right .under-content p:last-child {
  margin: 0;
}

/* images CSSここから */

.moderate .under-right img {
  width: 100%;
}

.moderate .image-right, .moderate .image-left {
  margin: 0 !important;
}

.moderate .image-right img, .moderate .image-left img {
  width: 340px;
}

.moderate .image-right img {
  margin: 0 0 0 15px;
}

.moderate .image-left img {
  margin: 0 15px 0 0;
}

@media only screen and (max-width: 640px) {
  .moderate .under-right img {
    width: 100%;
    margin: 0 0 2.5%;
  }
  .moderate .image-right, .moderate .image-left {
    width: 100%;
    margin: 0 !important;
  }
  .moderate .image-right img, .moderate .image-left img {
    display: block;
    width: 50% !important;
    margin: 0 auto 2.5%;
  }
}



@media only screen and (max-width: 640px) {
  .moderate .under-visual span.moderate {
    background: none;
    height: auto;
  }
}

/* margin CSSここから */

.m_top_20 {
  margin-top: 20px !important;
}

.m_top_40 {
  margin-top: 40px !important;
}

.m_top_60 {
  margin-top: 60px !important;
}

.m_bottom_10 {
  margin-bottom: 10px !important;
}

@media only screen and (max-width: 640px) {
  .m_top_40 {
    margin-top: 20px !important;
  }
  .m_top_60 {
    margin-top: 20px !important;
  }
  .m_bottom_10 {
    margin-bottom: 0px !important;
  }
}

/* 監修 CSSここから */

.supervision {
  margin: 0 0 30px;
}

@media only screen and (max-width: 640px) {
  .supervision {
    margin: 0 0 10%;
    padding: 0 2.5%;
    line-height: 2.2;
  }
}

.supervision dt {
  display: inline;
  background: #299eac;
  color: #FFF;
  margin-right: 10px;
  padding: 6px 8px 2px;
  -moz-border-radius: 3px;
  -webkit-border-radius: 3px;
  border-radius: 3px;
  font-size: 100%;
}

@media only screen and (max-width: 640px) {
  .supervision dt {
    display: block;
    width: 30px;
    padding: 1% 2%;
    margin: 0 1% 0 0;
    text-align: center;
  }
}

.supervision dd {
  display: inline;
  margin: 0;
  padding: 0;
  border: 0;
  font: inherit;
  font-size: 100%;
  vertical-align: baseline;
}

/* 参照 CSSここから */

.bibliography {
  font-size: 75%;
  margin: 20px 0;
  line-height: 1.5;
}

/* STUDYNOTE CSSここから */

.study_note {
  border: 2px solid #eb566d;
  background: #fdeff1;
  border-radius: 10px;
  overflow: hidden;
  margin: 0 0 20px;
}

.study_note h3 {
  background-color: #eb566d !important;
  color: #fff !important;
  padding: 15px;
  margin: 0 !important;
  line-height: 1.5;
}

.study_note h4 {
  color: #eb566d !important;
  padding: 15px 15px 5px;
  margin: 0 !important;
  line-height: 1.5;
  font-size: 20px;
}

.study_note h4:before {
  content: none;
}

.study_note h5 {
  color: #eb566d !important;
  margin: 0 15px !important;
  background: none !important;
  padding: 15px 0 0;
  line-height: 1.5;
  font-size: 20px;
  border-top: none !important;
  border-left: none !important;
  border-right: none !important;
  border-bottom: dotted 2px #eb566d;
  border-radius: 0 !important;
}

.study_note p {
  margin: 0 !Important;
  padding: 15px;
}

.study_note .image-right, .study_note .image-left {
  width: 310px;
}

.study_note .image-right {
  margin: 15px 15px 0 0 !important;
}

.study_note .image-left {
  margin: 15px 0 0 15px !important;
}

.study_note img {
  width: 100% !important;
  margin: 0 !important;
}

.study_note figure {
  padding: 15px;
}

.study_note figcaption {
  margin: 0 0 15px;
}

.study_note .graph_overview {
  font-size: 75%;
  margin: 15px 0;
  padding: 0 15px;
}

.study_note .graph_overview dt {
  display: inline-block;
  background: #eb566d;
  color: #fff;
  padding: 0 10px;
  border-radius: 5px;
  margin: 0 0 15px;
}

@media only screen and (max-width: 640px) {
  .study_note {
    margin: 0 10px 30px;
    overflow: hidden;
  }
  .study_note h3 {
    padding: 10px 12px !important;
    line-height: 1.4;
  }
  .study_note h4 {
    font-size: 16px;
    padding: 0 10px;
  }
  .study_note h5 {
    margin: 0 10px !important;
    padding: 0;
    font-size: 16px;
  }
  .study_note p {
    padding: 10px 12px !important;
  }
  .study_note img {
    margin: 0 auto !important;
  }
  .study_note .under-right h2:nth-of-type(1) {
    min-height: auto;
    margin: 0 0 2.5%;
  }
  .study_note .graph_overview dt {
    margin: 0;
  }
}

.study_note_list {
  padding: 15px;
}

.study_note_list>li {
  padding-left: 1em;
  text-indent: -1em;
}

.study_note_list>li:before {
  content: "";
  display: inline-block;
  width: 12px;
  height: 12px;
  border-radius: 6px;
  background: #eb566d;
  margin: 0 10px 0 0;
}

@media only screen and (max-width: 640px) {
  .study_note_list>li:before {
    width: 8px;
    height: 8px;
    border-radius: 4px;
  }
}

/* confirmation CSSここから */

.confirmation {
  margin: 70px 0 10px;
}

.confirmation_frame {
  padding: 5px 10px 10px;
  background: #ffffff;
  border: 2px solid #eb850d;
  -moz-border-radius: 10px;
  -webkit-border-radius: 10px;
  border-radius: 10px;
  margin-bottom: 10px;
}

.confirmation_head {
  display: inline-block;
  position: relative;
  top: -20px;
  padding: 15px 20px 10px;
  font-size: 24px;
  color: #ffffff;
  background: #eb850d;
  -moz-border-radius: 10px;
  -webkit-border-radius: 10px;
  border-radius: 10px;
}

.confirmation_title {
  font-size: 22px;
  padding: 0 0 10px 20px;
}

.confirmation_sub {
  font-size: 75%;
  padding: 0 0 0 30px;
}

.confirmation ul {
  display: flex;
  flex-wrap: wrap;
  margin-bottom: 10px;
}

.confirmation li {
  padding: 0 40px 5px 20px;
}

.confirmation li:before {
  content: "";
  display: inline-block;
  width: 12px;
  height: 12px;
  border-radius: 6px;
  background: #eb850d;
  margin: 0 10px 0 0;
}

@media only screen and (max-width: 640px) {
  .confirmation {
    margin: 20px 0;
  }
  .confirmation_head {
    font-size: 16px;
    font-weight: bold;
    padding: 10px 10px 10px;
  }
  .confirmation_title {
    font-size: 16px;
    padding: 0 0 10px 10px;
  }
  .confirmation_sub {
    font-size: 75%;
    padding: 0 0 0 0;
  }
  .confirmation li {
    padding: 0 30px 5px 10px;
  }
  .confirmation li:before {
    width: 8px;
    height: 8px;
    border-radius: 4px;
  }
}

/* index.html CSSここから */

.moderate_pagelink {
  clear: both;
  overflow: hidden;
}

.moderate_pagelink a:after {
  content: "";
  display: inline-block;
  width: 0;
  height: 0;
  border-style: solid;
  border-width: 8px 0 8px 10px;
  border-color: transparent transparent transparent #299eac;
  margin: 0 0 -1px 10px;
}

@media only screen and (max-width: 640px) {
  .lifestage_pagelink a:after {
    content: "";
    display: inline-block;
    width: 0;
    height: 0;
    border-style: solid;
    border-width: 1.4vw 0 1.4vw 1.8vw;
    border-color: transparent transparent transparent #299eac;
    margin: 0 0 -0.5% 1vw;
  }
  .lifestage_pagelink a {
    padding: 2% 3% 1%;
  }
}

.moderate_pdf a {
  display: inline-block;
  border: 1px solid #299eac;
  padding: 6px 15px 3px;
  border-radius: 10px;
  text-decoration: none !Important;
}

.moderate_pdf a:before {
  content: '';
  /*何も入れない*/
  display: inline-block;
  /*忘れずに！*/
  width: 32px;
  /*画像の幅*/
  height: 32px;
  /*画像の高さ*/
  background-size: contain;
  vertical-align: middle;
}

/* arthropathy.html CSSここから */

.moderate-frame1 dt {
  display: block;
  background: #299eac;
  color: #fff;
  padding: 5px 10px 2px;
  border-radius: 10px 10px 0 0;
  border: 2px solid #299eac;
  text-align: center;
  box-sizing: border-box;
}

.moderate-frame1 dd {
  border: 2px solid #299eac;
  padding: 15px;
  overflow: hidden;
  background: #fff;
  border-radius: 0 0 10px 10px;
  margin: 0 0 30px;
  box-sizing: border-box;
}

.moderate-frame1 img {
  width: 560px;
  margin: 0 auto;
  display: block;
}

.point_title {
  font-size: 18px !important;
  width: 26%;
  color: #299eac;
  border: 2px solid #299eac;
  padding: 5px 0 2px;
  background: #d8ecef;
  text-align: center;
  margin: 20px 0 10px !important;
  box-sizing: border-box;
}

.moderate-frame2 dt {
  display: block;
  background: #eb850d;
  color: #fff;
  padding: 5px 10px 2px;
  border-radius: 10px 10px 0 0;
  border: 2px solid #eb850d;
  text-align: center;
  box-sizing: border-box;
}

.moderate-frame2 dd {
  border: 2px solid #eb850d;
  padding: 15px;
  overflow: hidden;
  background: #fff;
  border-radius: 0 0 10px 10px;
  margin: 0 0 30px;
  box-sizing: border-box;
}

.moderate-frame2 li {
  padding-left: 1em;
  text-indent: -1em;
}

.moderate-frame2 li:before {
  content: "";
  display: inline-block;
  width: 12px;
  height: 12px;
  border-radius: 6px;
  background: #eb850d;
  margin: 0 10px 0 0;
}

@media only screen and (max-width: 640px) {
  .moderate-frame2 li:before {
    width: 8px;
    height: 8px;
    border-radius: 4px;
  }
  .point_title {
    font-size: 14px !important;
    width: 100%;
    padding: 0 !important;
  }
}

/* support.html CSSここから */

.support-team {
  overflow: hidden;
}

.support-team li {
  width: 47.5%;
  float: left;
  margin: 0 0 25px;
}

.support-team li:nth-child(2n) {
  float: right;
}

.support-team li span {
  display: block;
  color: #299eac;
  font-weight: bold;
  text-align: center;
}

.support-team img {
  width: 100%;
  display: block;
  margin: 0 auto;
}

/* manga.html */
.manga_cover {
  width: 60%;
  text-align: center;
  margin: auto;
}
.manga_read_btn {
  margin-top: 20px !important;
  background-color: #299eac;
  border-radius: 10px;
  color: #fff;
  padding: 5px 0;
}
.manga_cover a:hover img, .manga_cover a:hover p{
  opacity: 0.6;
}

.manga_content {
  width: 540px;
  margin: 0 50px;
  position: relative;
}

.manga_slid {}

.manga_slid li img {
  max-width: 92%;
  height: auto;
  margin: auto;
}

.slide-arrow{
  position: absolute;
  top: 50%;
}
.prev-arrow{
  right: -50px;
}
.next-arrow{
  left: -50px;
}


@media only screen and (max-width: 640px) {
  .manga_content {
    width: 100%;
    margin: 0;
  }
  .manga_slid li img {
    max-width: 100%;
  }
  .prev-arrow{
    right: 0px;
    width: 20px;
  }
  .next-arrow{
    left: 0px;
    width: 20px;
  }
}